Asian Journal of Pharmaceutical Sciences    2008, 3(5): 217-232   ISSN: 1818-0876   CN:    

 
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Recent developments in the analytical determination of cefadroxil
M. Espinosa Bosch1, A.J. Ruiz Sánchez2, F. Sánchez Rojas3*, C. Bosch Ojeda3
1 Department of Pharmacy, General Hospital, University Hospital “Virgen del Rocío”, Manuel Siurot s/n, 41013, Sevilla, Spain
2 Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Campus Teatinos s/n, 29071, Málaga, Spain
3 Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, Campus Teatinos s/n, 29071 Málaga, Spain
Received ; Revised ; Accepted ; Online 2008-10-30

Abstract

Abstract Cefadroxil is an orally active semi-synthetic β-lactam antibiotic from the cephalosporin group, characterized by its prolonged action. This compound is effective against susceptible bacteria causing infections of the urinary tract, skin and soft tissue as well as pharyngitis and laryngitis.
A variety of analytical methods have been proposed for the determination of cefadroxil in biological fluids and pharmaceutical samples. This review includes the most relevant analytical methodologies used for its determination in recent years.



Keywords:  Cefadroxil   Antibiotics   Biological and pharmaceutical samples   Review  

DOI: 

Correponding author: F. Sánchez Rojas; Email: fsanchezr@uma.es