Abstract

1 Department of Pharmacy, General Hospital, University Hospital “Virgen del Rocío”, Sevilla, Spain
2 Department of Organic Chemistry, Faculty of Sciences, University of Málaga, Málaga, Spain
3 Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, Málaga, Spain

Received 2009-3-6 ; Revised 2009-5-14 ; Accepted 2009-7-6 ; Online 2009-9-10

Abstract

Ganciclovir (GCV) is a nucleoside analogue of guanosine that exhibits antiviral activity against viruses of the herpes group, including cytomegalovirus. GCV is an effective therapy for cytomegalovirus infection in immunocompromised patients, such as patients with acquired immunodeficiency syndrome or those with immunosuppressive therapy following organ transplantation. The present article reviews the published methods for the determination of GCV.

Keywords: Ganciclovir Review Biological samples HPLC

DOI:

Correponding author: F. Sánchez Rojas; Email: fsanchezr@uma.es